Comparison of online pharmacies by Drug: Generic Ventolin (Salbutamol)
What is Ventolin?
In the modern world, a huge number of ailments are known that must be dealt with as soon as the first symptoms appear. Stenosis is a quite often diagnosed disease, which implies a complete or partial narrowing of the airways as a result of which it becomes difficult for a person to breathe, and he/she runs out of air. If nothing is done, over time, the patient may develop oxygen deprivation as a result of which the normal functioning of all internal organs and systems will be disrupted.
One of the most effective and popular drugs used for the treatment of pathology is called Ventolin Inhaler for inhalation; instructions on the correct use for children will be described in detail later in this article. The main advantage of the drug over its analogs is that during the treatment, the side effects almost never occur. Therefore, the inhaler is often prescribed not only to the pre-school children but also to the babies. Let’s take a closer look at what this drug represents and what features it has.
Ventolin represents a drug whose action aims to stop the attacks of bronchial asthma and other reversible diseases with bronchial obstruction. The active substance of the drug is salbutamol (also known as albuterol).
Pharmacological action of Ventolin
According to Ventolin’s instruction, its active component affects beta-2 receptors, which causes the bronchi expansion in case of bronchospasm. The drug has an insignificant effect on beta-1 adrenergic receptors.
The antiallergic property of the reversible drug is explained by suppressing the release of histamine and other mediators from the mast cells. About 10-20% of the amount of Ventolin inhaled reaches the lower respiratory tract. Most of the dose, respectively, are deposited in the nasopharynx or delivery device. The necessary amount of the drug penetrates into the systemic blood flow, while the process of metabolism of the drug doesn’t occur in the lungs. Binding to the blood proteins is performed by 10%.
The action of Ventolin starts a few minutes after inhalation and lasts 4-6 hours. The drug is excreted by the liver with urine (90%) in its original form and in the form of a phenol sulfate compound. The drug also leaves the body with bile. The majority of the drug is excreted within 72 hours.
It should be taken into account that according to the instructions, Ventolin penetrates the placental barrier.
Indications for the use of Ventolin
According to the instruction, the main indicators for the use of Ventolin are:
- Bronchial asthma (in order to eliminate attacks);
- Bronchospasm attacks caused by physical exertion or allergic reactions;
- Obstructive pulmonary diseases, such as bronchitis, emphysema, and other (for long-term therapy).
Ways of use and dosages of Ventolin
In the case of bronchospasm, Ventolin Inhaler is prescribed to adult patients in the dose of 100-200 µg per dose. As a preventive measure, patients are prescribed 200 µg 3-4 times a day. If the patient is about to come into contact with an allergen or to go to work out, the recommended dose of this drug– 200 µg 15 minutes before the expected irritating effect. To stop attacks of bronchospasm in children, Ventolin must be used in the following doses: 2-6 years – 1-2 mg; 6-12 years – 2 mg;
Over the age of 12 – 2-4 mg. Prophylactic doses imply the use of 100-200 µg 3 times a day. Adult patients using the drug in the form of syrup should take 2 ml 3-4 times a day; however, if necessary, the dose can be increased to 4 ml.
Ventolin Inhaler can’t be used more often than 4 times within 24 hours. Elderly patients are recommended to stick to the dose of 2 mg 3 times a day. Ventolin is used for inhalations, while the dosages are as follows:
For adults: 2.5 mg up to 4 times a day, while the maximum allowable dose is 5 mg;
For children older than 1.5 years: max 2.5 mg up to 4 times a day.
Side effects of Ventolin
According to the instructions, Ventolin has the following side effects:
- Minor tremors of the limbs (hands);
- Expansion of blood vessels and increased heart rate;
- Paradoxical bronchospasm;
- Agitation and excessive increase of activity in children;
- Heart rhythm disorder;
- Allergic symptoms: bronchospasm, angioedema, and arterial hypotension.
Contraindications to the use of Ventolin
The drug is contraindicated in case of hypersensitivity to its components and during pregnancy with complications. Ventolin Inhaler is prescribed very carefully during lactation because the issue of drug safety for babies is not studied enough.
Ventolin can’t be combined with non-selective beta-blockers. It enhances the effect of the drugs stimulating the central nervous system. It also increases the risk of developing arrhythmia against the background of the use of cardiac glycosides. The medication is not contraindicated to the patients using MAO inhibitors.
The risk of developing tachyarrhythmia increases if you take theophylline and other xanthines at the same time.
The combination of the drug with the medications for inhalation pain relief and levodopa can provoke ventricular arrhythmias. Simultaneous use of anticholinergics can cause an increase in intraocular pressure. Such a side effect of Ventolin as hypokalemia may increase if you use diuretics and glucocorticosteroids.
Treatment of bronchial asthma should be carried out step by step while monitoring the patient’s clinical response to the treatment and lung function.
In case of severe or unstable bronchial asthma, it is forbidden to use Ventolin as a monotherapy.
Suppose the patient is increasingly using short-acting bronchodilators to relieve the symptoms of bronchial asthma. In that case, this indicates a deterioration in the course of pathology. In this case, you should see a doctor revise the treatment regimen.
If the duration of the drug effect after the inhalation is less than 3 hours, you need to consult the doctor.
If the recommended doses are exceeded, the following symptoms of overdose may be observed:
- drop in blood pressure;
- heart palpitations;
- trembling in certain parts of the body;
- a decrease in the level of potassium in the blood.
When these signs of drug poisoning appear, you need to cancel therapy and prescribe symptomatic treatment. If the patient has cardiac symptoms and heart palpitations, cardioselective beta-blockers are prescribed. They must be used with caution if the patient has a history of bronchospasm.
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